Prevalence of chronic kidney disease in China: a cross-sectional survey

Prevalence of chronic kidney disease in China: a cross-sectional survey

BACKGROUND

The prevalence of chronic kidney disease is excessive in creating international locations. However, no nationwide survey of chronic kidney disease has been completed incorporating each estimated glomerular filtration charge (eGFR) and albuminuria in a creating nation with the financial range of China. We aimed to measure the prevalence of chronic kidney disease in China with such a survey.

METHODS

We did a cross-sectional survey of a nationally consultant pattern of Chinese adults. Chronic kidney disease was outlined as eGFR lower than 60 mL/min per 1·73 m(2) or the presence of albuminuria.

Participants accomplished a life-style and medical historical past questionnaire and had their blood stress measured, and blood and urine samples taken. Serum creatinine was measured and used to estimate glomerular filtration charge. Urinary albumin and creatinine had been examined to evaluate albuminuria.

The crude and adjusted prevalence of indicators of kidney harm had been calculated and elements related to the presence of chronic kidney disease analysed by logistic regression.RESULTS50,550 individuals had been invited to take part, of whom 47,204 agreed.

The adjusted prevalence of eGFR lower than 60 mL/min per 1·73 m(2) was 1·7% (95% CI 1·5-1·9) and of albuminuria was 9·4% (8·9-10·0). The general prevalence of chronic kidney disease was 10·8% (10·2-11·3); due to this fact the quantity of sufferers with chronic kidney disease in China is estimated to be about 119·5 million (112·9-125·Zero million).

Prevalence of chronic kidney disease in China: a cross-sectional survey
Prevalence of chronic kidney disease in China: a cross-sectional survey

In rural areas, financial improvement was independently related to the presence of albuminuria. The prevalence of chronic kidney disease was excessive in north (16·9% [15·1-18·7]) and southwest (18·3% [16·4-20·4]) areas in contrast with different areas.

Other elements independently related to kidney harm had been age, intercourse, hypertension, diabetes, historical past of cardiovascular disease, hyperuricaemia, space of residence, and financial standing.CONCLUSIONSChronic kidney disease has turn into an essential public well being drawback in China. S

pecial consideration must be paid to residents in economically bettering rural areas and particular geographical areas in China.

BACKGROUND

The Ministry of Science and Technology (China); the Science and Technology Commission of Shanghai; the National Natural Science Foundation of China; the Department of Health, Jiangsu Province; the Sichuan Science and Technology Department; the Ministry of Education (China); the International Society of Nephrology Research Committee; and the China Health and Medical Development Foundation.

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